Calmodulin activates Cam-PDE 1

Stable Identifier
R-HSA-111956
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Increased Ca2+ levels, acting via calmodulin, can activate PDE which can then act upon cAMP.

Literature References
PubMed ID Title Journal Year
18335582 Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+

Goraya, TA, Masada, N, Ciruela, A, Willoughby, D, Clynes, MA, Cooper, DM

Cell Signal 2008
15272012 Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A

Goraya, TA, Masada, N, Ciruela, A, Cooper, DM

J Biol Chem 2004
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