PKA-mediated phosphorylation of CREB

Stable Identifier
R-HSA-111931
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Pathway
Species
Homo sapiens
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Cyclic adenosine 3',5'-monophosphate (cAMP) induces gene transcription through activation of cAMP-dependent protein kinase (PKA), and subsequent phosphorylation of the transcription factor cAMP response element-binding protein, CREB, at serine-133.

Literature References
PubMed ID Title Journal Year
15337521 What turns CREB on?

Johannessen, M, Delghandi, MP, Moens, U

Cell Signal 2004
16125054 The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells

Delghandi, MP, Johannessen, M, Moens, U

Cell Signal 2005
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