CAMK4 autophosphorylates

Stable Identifier
R-HSA-111915
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Autophosphorylation of the N-terminal serine residues, S12 and S13, of CAMK4 is required for full activation after Ca2+/calmodulin binding and phosphorylation of the Ca2+/calmodulin-bound enzyme on threonine residue T200 by a Ca2+/calmodulin-dependent protein kinase kinase (CAMKK1 or CAMKK2) (Chatila et al. 1996).

Literature References
PubMed ID Title Journal Year
8702940 A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR

Chatila, T, Anderson, KA, Ho, N, Means, AR

J Biol Chem 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
calmodulin-dependent protein kinase activity of p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created