Docking of Mature Histone mRNA complex:TAP at the NPC

Stable Identifier
R-HSA-111439
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Histone mRNAs are exported by a mechanism that requires TAP, the key factor required for transport of polyadenylated mRNAs. How TAP is recruited to the histone mRNAs is not known, but it is clear that transport can occur in the absence of either the stemloop or of SLBP. The mature transcript docks at the NPC. In the course of transport, CBC is lost from the mRNA cap, and remain in the nucleous.
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