Reactome | Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

Stable Identifier

R-HSA-111289

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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PRPP stimulates the dissociation of phosphoribosyl pyrophosphate amidotransferase tetramers to form dimers (Holmes et al. 1973a,b).

Literature References

PubMed ID	Title	Journal	Year
4348202	Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties Holmes, EW, McDonald, JA, McCord, JM, Wyngaarden, JB, Kelley, WN	J Biol Chem	1973
4726295	Human glutamine phosphoribosylpyrophosphate amidotransferase. Two molecular forms interconvertible by purine ribonucleotides and phosphoribosylpyrophosphate Holmes, EW, Wyngaarden, JB, Kelley, WN	J Biol Chem	1973