Reactome | Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer

Stable Identifier

R-HSA-111289

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

PRPP stimulates the dissociation of phosphoribosyl pyrophosphate amidotransferase tetramers to form dimers (Holmes et al. 1973a,b).

Literature References

PubMed ID	Title	Journal	Year
4726295	Human glutamine phosphoribosylpyrophosphate amidotransferase. Two molecular forms interconvertible by purine ribonucleotides and phosphoribosylpyrophosphate Holmes, EW, Wyngaarden, JB, Kelley, WN	J Biol Chem	1973
4348202	Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties Holmes, EW, McDonald, JA, McCord, JM, Wyngaarden, JB, Kelley, WN	J Biol Chem	1973