Reactome | PRDM14 [nucleoplasm]

PRDM14 [nucleoplasm]

Stable Identifier

R-HSA-1112608

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PR domain zinc finger protein 14, PRD14_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9GZV8 PRDM14

Gene Names

PRDM14

Chain

chain:1-571

Reference Genes

BioGPS Gene:63978 PRDM14

COSMIC (genes):PRDM14 PRDM14

CTD Gene:63978 PRDM14

dbSNP Gene:63978 PRDM14

ENSEMBL:ENSG00000147596 PRDM14

HGNC:14001 PRDM14

KEGG:hsa:63978 PRDM14

Monarch:63978 PRDM14

NCBI Gene:63978 PRDM14

OMIM:611781 PRDM14

UCSC:Q9GZV8 PRDM14

Reference Transcript

RefSeq:NM_024504.3 PRDM14

Other Identifiers

11734156_at

17078048

220714_PM_at

220714_at

3139691

3139692

3139694

3139696

3139697

3139698

3139699

3139700

3139701

3139702

3139703

3139704

3139705

3139707

3139708

3139709

3139710

3139711

63978

8151240

A_23_P123488

GE82841

GO:0000122

GO:0000902

GO:0000977

GO:0001708

GO:0001827

GO:0003677

GO:0003723

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0006325

GO:0006355

GO:0006357

GO:0007281

GO:0007566

GO:0008168

GO:0008543

GO:0009566

GO:0010468

GO:0016740

GO:0019827

GO:0022414

GO:0030718

GO:0031490

GO:0032259

GO:0040029

GO:0040037

GO:0043226

GO:0043231

GO:0045814

GO:0046872

GO:0048856

GO:0048873

GO:0060818

GO:0098772

GO:0141107

GO:1902093

GO:1902459

GO:1990226

HMNXSV003027655

ILMN_1815120

ILMN_2163835

PH_hs_0014866

TC08001307.hg

g13375635_3p_at

Participates

as an input of

POU5F1 (OCT4), SOX2, NANOG, ZSCAN10, PRDM14, SMAD2, FOXP1-ES bind the POU5F1 (OCT4) promoter (Homo sapiens)

as a component of

POU5F1:SOX2:NANOG:ZSCAN10:PRDM14:SMAD2:SALL4:FOXP1-ES:POU5F1 gene [nucleoplasm] (Homo sapiens)

Inferred To

PRDM14 [nucleoplasm] (Gallus gallus)

PRDM14 [nucleoplasm] (Mus musculus)

PRDM14 [nucleoplasm] (Sus scrofa)

Prdm14 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_078780.1

OpenTargets

ENSG00000147596

ENSEMBL

ENST00000276594, ENSP00000276594

HPA

ENSG00000147596-PRDM14

PRO

Q9GZV8

Pharos - Targets

Q9GZV8

Interactors (65)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43439 CBFA2T2	1	CBFA2T2 [nucleoplasm] (R-HSA-9827884)	0.856	14
UniProt:Q8N5M1 ATPF2			0.849	10
UniProt:Q8WW24 TEKT4			0.718	6
UniProt:P98175 RBM10	1	RBM10 [nucleoplasm] (R-HSA-9770262)	0.718	6
UniProt:Q96GN5 CDA7L			0.718	6
UniProt:O43439-4 CBFA2T2			0.666	6
UniProt:Q96MH2 HEXI2			0.666	4
UniProt:Q06455-2 RUNX1T1			0.666	6
UniProt:O43741 PRKAB2	2	PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [nucleoplasm] (R-HSA-164096)	0.666	4
UniProt:P09022 Hoxa1	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.57	3
UniProt:Q9UBY9 HSPB7			0.556	3
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.556	3
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.556	3
UniProt:Q86UY5 FAM83A	1	FAM83A [cytosol] (R-HSA-9851391)	0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:Q7Z5V6-2 SAXO4			0.556	3
UniProt:Q9BYC8 MRPL32	2	MRPL32 [mitochondrial inner membrane] (R-HSA-5368195) MRPL32 [mitochondrial matrix] (R-HSA-9839664)	0.556	3
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:Q02930-3 CREB5			0.556	3
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.556	3
UniProt:Q5I0X7 TTC32			0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:O75771 RAD51D	1	RAD51D [nucleoplasm] (R-HSA-216920)	0.556	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:Q9NYB9-2 ABI2			0.556	3
UniProt:Q8IVS8 GLYCTK	1	GLYCTK [cytosol] (R-HSA-6799244)	0.556	3
UniProt:Q9Y2P0 ZN835			0.556	3
UniProt:Q5JRA6-2 MIA3			0.556	3
UniProt:P15622-3 ZNF250			0.556	3
UniProt:Q9Y4C2-2 TCAF1			0.556	3
UniProt:Q9BZW7 TSG10			0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:Q9P2K3 RCOR3			0.556	3
UniProt:P42681 TXK	3	TXK [cytosol] (R-HSA-3448733) p-Y91,Y420-TXK [cytosol] (R-HSA-3448740) p-Y420-TXK [cytosol] (R-HSA-3448734)	0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	5
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q8WV44 TRIM41	1	TRIM41 [cytosol] (R-HSA-5688975)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:P09067 HXB5			0.556	3
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:Q99996-2 AKAP9			0.556	3
UniProt:O60573 EIF4E2	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
UniProt:Q9BWT7 CAR10			0.556	3
UniProt:Q8TBE0 BAHD1			0.556	3
UniProt:Q9NWQ4 GPT2L			0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:Q9NWQ4-1 GPATCH2L			0.556	3
UniProt:Q9BWG6 SCNM1			0.556	5
UniProt:Q9HBE1-4 PATZ1			0.556	3
UniProt:Q08117-2 TLE5			0.556	5
UniProt:Q64LD2-2 WDR25			0.556	3
UniProt:Q06455-4 RUNX1T1			0.556	3
UniProt:Q9BXY8 BEX2			0.556	3
UniProt:Q06455 MTG8			0.547	3
UniProt:Q9ULQ0 STRP2			0.527	2
UniProt:Q8WZ74 CTTB2			0.527	2
UniProt:Q9P2B4 CT2NL			0.527	2
UniProt:Q5VSL9 STRP1			0.527	2
UniProt:O75081 MTG16			0.527	3
UniProt:Q13033 STRN3			0.527	3
UniProt:Q9NRL3 STRN4			0.527	3
UniProt:O43815 STRN	5	STRN [cytosol] (R-HSA-9037081) STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908) STRN(1-137)-ALK(1058-1620) fusion [cytosol] (R-HSA-9700485) STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9700467)	0.527	2

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