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p-Y701-STAT1, p-Y705-STAT3 [cytosol]
Stable Identifier
R-HSA-1112571
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:p(Y701)-STAT1/p(Y705)-STAT3 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-6 family signaling (Homo sapiens)
Interleukin-6 signaling (Homo sapiens)
Phosphorylated STAT1, STAT3 form dimers (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Phosphorylated STATs are released (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Serine phosphorylation of STATs (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3 [cytosol] (Homo sapiens)
Participants
members
p-Y705-STAT3 [cytosol]
(Homo sapiens)
p-Y701-STAT1 [cytosol]
(Homo sapiens)
Participates
as a component of
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:p(Y701)-STAT1/p(Y705)-STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
as an output of
FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)
Phosphorylated STATs are released (Homo sapiens)
as an input of
Phosphorylated STAT1, STAT3 form dimers (Homo sapiens)
Inferred To
phospho-stat1a [cytosol]
(Danio rerio)
phospho-Stat92E [cytosol]
(Drosophila melanogaster)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Bos taurus)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Caenorhabditis elegans)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Canis familiaris)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Dictyostelium discoideum)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Gallus gallus)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Mus musculus)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Rattus norvegicus)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Sus scrofa)
p-Y701-STAT1, p-Y705-STAT3 [cytosol]
(Xenopus tropicalis)
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