Recruitment of POLB to the AP site

Stable Identifier
R-HSA-110360
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Recruitment of POLB to the AP site
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APEX1 (APE1) bound to the apurinic/apyrimidinic site (AP site) in the DNA recruits DNA polymerase beta (POLB) into a ternary complex (Bennett et al. 1997).

Literature References
PubMed ID Title Journal Year
9207062 Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway.

Wilson, DM, Wong, D, Bennett, RA, Demple, B

Proc Natl Acad Sci U S A 1997
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Authored
Matthews, L  (2004-02-03)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Matthews, L  (2004-01-29)
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