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Reactome Pathway Database

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LIG3:XRCC1:POLB:SSB-gap-dsDNA

Stable Identifier
R-HSA-110339
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
LIG3:XRCC1:POL Beta complex at site of base repair
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
    • Base Excision Repair (Homo sapiens)
      • Resolution of Abasic Sites (AP sites) (Homo sapiens)
        • Resolution of AP sites via the single-nucleotide replacement pathway (Homo sapiens)
          • Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Homo sapiens)
            • LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Homo sapiens)
          • Resynthesis of excised residue by POLB (Homo sapiens)
            • LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Homo sapiens)
Participants
components
  • LIG3:XRCC1 [nucleoplasm] (Homo sapiens)
  • POLB:SSB-gap-dsDNA [nucleoplasm] (Homo sapiens)
Participant Of
input
  • Resynthesis of excised residue by POLB
output
  • Recruitment of LIG3:XRCC1 complex to the site of repair by POLB
Inferred To
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Bos taurus)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Canis familiaris)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Danio rerio)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Dictyostelium discoideum)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Mus musculus)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Rattus norvegicus)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Sus scrofa)
LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm] (Xenopus tropicalis)

 

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