Cleavage of the damaged purine

Stable Identifier
R-HSA-110331
Type
Pathway
Species
Homo sapiens
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Damaged purines are cleaved from the sugar-phosphate backbone by purine-specific glycosylases (Saparbaev and Laval 1994, Lindahl and Wood 1999).

Literature References
PubMed ID Title Journal Year
8016081 Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases

Saparbaev, M, Laval, J

Proc. Natl. Acad. Sci. U.S.A. 1994
10583946 Quality control by DNA repair

Lindahl, T, Wood, RD

Science 1999
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