Cleavage of hypoxanthine by MPG glycosylase

Stable Identifier
R-HSA-110251
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

MPG, 3-methyladenine DNA glycosylase, cleaves the alkylated DNA base hypoxanthine (Saparbaev and Laval 1994).

Literature References
PubMed ID Title Journal Year
8016081 Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases

Saparbaev, M, Laval, J

Proc. Natl. Acad. Sci. U.S.A. 1994
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
DNA N-glycosylase activity of MPG:Hyp-dsDNA [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
Cite Us!