TDG glycosylase mediated recognition and binding of an ethenocytosine

Stable Identifier
R-HSA-110210
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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TDG glycosylase mediated recognition and binding of an ethenocytosine
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TDG, a G/T mismatch-specific DNA glycosylase, recognizes and binds ethenocytosine paired with guanine. Ethenocytosine is an etheno-adduct of cytosine, generated by peroxidation of the cytosine ring (Hang et al. 1998).

Literature References
PubMed ID Title Journal Year
9811839 A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch

Singer, B, Hang, B, Fraenkel-Conrat, H, Medina, M

Proc. Natl. Acad. Sci. U.S.A. 1998
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as an event of
Authored
Matthews, L  (2004-02-03)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Matthews, L  (2004-01-29)
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