Reactome | SMUG1 [nucleoplasm]

SMUG1 [nucleoplasm]

Stable Identifier

R-HSA-110161

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hSMUG1 glycosylase

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q53HV7 SMUG1

Gene Names

SMUG1

Chain

chain:1-270

Reference Genes

BioGPS Gene:23583 SMUG1

COSMIC (genes):SMUG1 SMUG1

CTD Gene:23583 SMUG1

dbSNP Gene:23583 SMUG1

ENSEMBL:ENSG00000123415 SMUG1

HGNC:17148 SMUG1

KEGG:hsa:23583 SMUG1

Monarch:23583 SMUG1

NCBI Gene:23583 SMUG1

OMIM:607753 SMUG1

UCSC:Q53HV7 SMUG1

Reference Transcript

Participates

as an output of

Displacement of SMUG1 glycosylase by APEX1 at the AP site (Homo sapiens)

as a component of

as an input of

SMUG1 glycosylase mediated recognition and binding of uracil in DNA (Homo sapiens)

Inferred To

SMUG1 [nucleoplasm] (Bos taurus)

SMUG1 [nucleoplasm] (Canis familiaris)

SMUG1 [nucleoplasm] (Gallus gallus)

SMUG1 [nucleoplasm] (Sus scrofa)

smug1 [nucleoplasm] (Danio rerio)

smug1 [nucleoplasm] (Xenopus tropicalis)

Smug [nucleoplasm] (Drosophila melanogaster)

Smug1 [nucleoplasm] (Mus musculus)

Smug1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

XP_047284591.1, NP_001230719.1, XP_054227596.1, NP_001338170.1, XP_016874602.1, XP_016874606.1, XP_054227608.1, XP_011536418.1, NP_001338172.1, NP_001338176.1, NP_001338168.1, XP_047284594.1, XP_054227619.1, XP_011536419.1, XP_016874607.1, XP_011536421.1, NP_001338185.1, XP_054227605.1, XP_011536420.1, NP_001338177.1, NP_001338182.1, XP_054227611.1, XP_054227597.1, XP_011536417.1, XP_011536422.1, XP_047284608.1, NP_001230717.1, XP_047284605.1, NP_001338178.1, NP_001338184.1, XP_054227607.1, XP_047284602.1, XP_047284593.1, XP_047284595.1, XP_054227623.1, NP_001338174.1, XP_054227618.1, NP_001230716.1, XP_054227614.1, XP_054227613.1, XP_054227602.1, XP_016874609.1, NP_001338181.1, XP_016874603.1, XP_047284596.1, XP_011536411.1, XP_054227609.1, NP_001338167.1, NP_001338171.1, XP_011536424.1, XP_047284604.1, NP_001338173.1, XP_047284597.1, XP_011536416.1, XP_054227612.1, XP_054227622.1, NP_001338180.1, XP_047284607.1, XP_047284609.1, XP_054227616.1, XP_047284599.1, XP_054227600.1, XP_054227606.1, XP_016874605.1, XP_054227598.1, XP_047284592.1, NP_001338183.1, XP_054227617.1, NP_001230718.1, NP_001338179.1, XP_054227601.1, XP_047284588.1, XP_054227615.1, XP_006719385.1, XP_006719383.1, XP_016874608.1, XP_054227610.1, XP_054227604.1, XP_011536423.1, XP_047284610.1, XP_006719382.1, NP_001230720.1, NP_055126.1, XP_047284601.1, XP_011536414.1, NP_001338166.1, NP_001338191.1, XP_047284611.1, XP_047284598.1, XP_011536413.1, XP_006719384.1, XP_011536415.1, XP_047284589.1, XP_054227621.1, NP_001338175.1, XP_047284606.1, NP_001338169.1, XP_047284600.1, XP_047284590.1, NP_001338186.1, XP_054227620.1, XP_016874604.1, XP_054227595.1, XP_054227603.1, XP_054227599.1, XP_011536412.1

OpenTargets

ENSG00000123415

ENSEMBL

ENST00000514685, ENSG00000123415, ENST00000682136, ENST00000513838, ENSP00000423629, ENSP00000243112, ENST00000401977, ENSP00000421139, ENSP00000338606, ENSP00000421206, ENST00000506595, ENSP00000424191, ENST00000508394, ENST00000337581, ENST00000243112, ENSP00000384828, ENSP00000507590

HPA

ENSG00000123415-SMUG1

GeneCards

SMUG1

PRO

Q53HV7

Pharos - Targets

Q53HV7

HMDB Protein

HMDBP12343

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.666	4
UniProt:O43186 CRX			0.556	3
UniProt:P12757 SKIL	1	SKIL [nucleoplasm] (R-HSA-2186596)	0.556	3
UniProt:Q9UJX2 CDC23	2	CDC23 [cytosol] (R-HSA-174137) CDC23 [nucleoplasm] (R-HSA-174228)	0.556	3
UniProt:Q93062 RBPMS			0.508	2

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