Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA

Stable Identifier
R-HSA-109998
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Once the second of the two double bonds has been reached 3,2-trans-enoyl-CoA isomerase, changes the spatial conformation of the second double bond from cis to trans. This step yields trans-dec-2-enoyl-CoA, which then enters the saturated beta-oxidation pathway.
Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Catalyst Activity

intramolecular oxidoreductase activity of DCI dimer [mitochondrial matrix]

Physical Entity
DCI dimer [mitochondrial matrix] (Homo sapiens)
Activity
intramolecular oxidoreductase activity (GO:0016860)
Orthologous Events
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Bos taurus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Canis familiaris)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Drosophila melanogaster)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Gallus gallus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Mus musculus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Rattus norvegicus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Sus scrofa)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Xenopus tropicalis)
Cross References
Rhea
Authored
Gillespie, ME  (2004-01-19)
Created
Gillespie, ME  (2004-01-19)
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