Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA

Stable Identifier
R-HSA-109998
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA
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Once the second of the two double bonds has been reached 3,2-trans-enoyl-CoA isomerase, changes the spatial conformation of the second double bond from cis to trans. This step yields trans-dec-2-enoyl-CoA, which then enters the saturated beta-oxidation pathway.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Catalyst Activity

intramolecular oxidoreductase activity of DCI dimer [mitochondrial matrix]

Physical Entity
DCI dimer [mitochondrial matrix] (Homo sapiens)
Activity
intramolecular oxidoreductase activity (GO:0016860)
Orthologous Events
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Bos taurus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Canis familiaris)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Danio rerio)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Drosophila melanogaster)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Gallus gallus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Mus musculus)
Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Rattus norvegicus)
Cross References
Rhea
Authored
Gillespie, ME  (2004-01-19)
Created
Gillespie, ME  (2004-01-19)
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