Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2

Stable Identifier
R-HSA-109864
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2
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MAP2K2 (MEK2) dissociates from phosphorylated MAPK1 (ERK2), allowing activated MAPK1 (ERK2) to dimerise (Zheng and Guang 1994).
Literature References
PubMed ID Title Journal Year
8131746 Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues

Zheng, CF, Guan, KL

EMBO J 1994
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Orthologous Events
Dissociation of phospho ERK2 :phospho MEK2 complex (Gallus gallus)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Caenorhabditis elegans)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Canis familiaris)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Danio rerio)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Dictyostelium discoideum)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Drosophila melanogaster)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Mus musculus)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Rattus norvegicus)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Sus scrofa)
Authored
Charalambous, M  (2005-02-04)
Reviewed
Gillespie, ME  (2010-11-24)
Created
Charalambous, M  (2004-04-29)
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