MAP2K2 phosphorylates MAPK1

Stable Identifier
R-HSA-109862
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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MAP2K2 (MEK2) phosphorylates MAPK1 (ERK2). Phosphorylation of MAPK1 activates its kinase activity.

Literature References
PubMed ID Title Journal Year
8388392 Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

Zheng, CF, Guan, KL

J Biol Chem 1993
22177953 MEK1/2 dual-specificity protein kinases: structure and regulation

Roskoski, R Jr

Biochem. Biophys. Res. Commun. 2012
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-S,T-MAP2K2:MAPK1 [cytosol]

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