At the beginning of this reaction, 4 molecules of 'ATP', and 1 molecule of 'GRB2:SOS:IRS-P' are present. At the end of this reaction, 1 molecule of 'GRB2:IRS-P', 1 molecule of 'phospho-SOS', and 4 molecules of 'ADP' are present. This reaction takes place on the 'internal side of plasma membrane' and is mediated by the 'kinase activity' of 'ERK1'.
Corbalan-Garcia, S, Yang, SS, Degenhardt, KR
Waters, SB, Yamauchi, K, Pessin, JE
protein serine/threonine kinase activity of MAPK3,(MAPK1) [cytosol]
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