Two specific sites in AKT2, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474), need to be phosphorylated for its full activation.
Baer, K, Lisinski, I, Gompert, M, Stuhlmann, D, Schmolz, K, Klein, HW, Al-Hasani, H
Stokoe, D, Stephens, LR, Copeland, T, Gaffney, PR, Reese, CB, Painter, GF, Holmes, AB, McCormick, F, Hawkins, PT
Alessi, DR, James, SR, Downes, CP, Holmes, AB, Gaffney, PR, Reese, CB, Cohen, P
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