Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1

Stable Identifier
R-HSA-109530
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane, extracellular region
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Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
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The plasma membrane-associated protein SLC28A1 mediates the transport of one molecule of 2'-deoxyadenosine, adenosine, cytidine, thymidine, or uridine, and one sodium ion, from the extracellular space to the cytosol.

Literature References
PubMed ID Title Journal Year
9124315 Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)

Huang, MY, Ritzel, MW, Elliott, JF, Young, JD, Cass, CE, Yao, SY

Am J Physiol Cell Physiol 1997
Participants
Input
Output
Participates
as an event of
Catalyst Activity

nucleoside:sodium symporter activity of SLC28A1 [plasma membrane]

Physical Entity
SLC28A1 [plasma membrane] (Homo sapiens)
Activity
nucleoside:sodium symporter activity (GO:0005415)
Orthologous Events
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Bos taurus)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Caenorhabditis elegans)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Danio rerio)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Drosophila melanogaster)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Gallus gallus)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Mus musculus)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Rattus norvegicus)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Sus scrofa)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Xenopus tropicalis)
Authored
D'Eustachio, P  (2004-01-13)
Reviewed
He, L  (2010-05-10)
Created
D'Eustachio, P  (2004-01-13)
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