Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA

Stable Identifier
R-HSA-109343
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA
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The second of the two accessory enzymes, 2,4-dienoyl-CoA reductase catalyses an oxidation-reduction (redox) reaction to yield 3-trans-decenoyl-CoA.
Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Scriver, CR, Beaudet, AL, Valle, D, Sly, WS

  2001
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Catalyst Activity

oxidoreductase activity, acting on NAD(P)H of DECR1 tetramer [mitochondrial matrix]

Physical Entity
DECR1 tetramer [mitochondrial matrix] (Homo sapiens)
Activity
oxidoreductase activity, acting on NAD(P)H (GO:0016651)
Orthologous Events
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Bos taurus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Caenorhabditis elegans)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Canis familiaris)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Gallus gallus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Mus musculus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Rattus norvegicus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Sus scrofa)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Xenopus tropicalis)
Authored
Gillespie, ME  (2004-01-19)
Created
Gillespie, ME  (2004-01-02)
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