5'-nucleotidase (NT5E) associated with the plasma membrane catalyzes the reactions of extracellular CMP, TMP, or UMP with H2O to yield the corresponding nucleoside and orthophosphate. The active enzyme is a glycolipid-anchored dimer (Misumi et al. 1990; Thompson et al. 1987; Zimmerman 1992)
Thompson, LF, Ruedi, JM, Clement, LT, Low, MG
Ogata, S, Ikehara, Y, Misumi, Y, Hirose, S, Ohkubo, K
Stone, CD
5'-nucleotidase activity of NT5E:Zn2+ dimer [plasma membrane]
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