Formation of VAF (virus-activated factor) complex

Stable Identifier
R-HSA-1028820
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Formation of VAF (virus-activated factor) complex
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IRF3 and IRF7 associate with each other and they further interact with the coactivators CBP and p300 to form a more potent transcription factor complex called VAF (virus-activated factor).

Literature References
PubMed ID Title Journal Year
9660935 Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

Ronco, LV, Wathelet, MG, Lin, CH, Maniatis, T, Howley, PM, Parekh, BS

Mol Cell 1998
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Orthologous Events
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Formation of VAF (virus-activated factor) complex (Sus scrofa)
Formation of VAF (virus-activated factor) complex (Xenopus tropicalis)
Authored
Garapati, P V  (2010-08-02)
Reviewed
Akira, S  (2010-10-30)
Kawai, T  (2010-10-30)
Created
Garapati, P V  (2010-11-18)
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