Translocation of phosphorylated IRF3,IRF7 dimers into nucleus

Stable Identifier
R-HSA-1028816
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
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Translocation of phosphorylated IRF3,IRF7 dimers into nucleus
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Phosphorylated IRF dimers after dimerization translocates into the nucleus and associate with general coactivators like CBP/p300 and bind to type-I IFN promoter region.
Literature References
PubMed ID Title Journal Year
12604599 Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators

Yang, H, Wathelet, MG, Ma, G, Lin, CH, Baffi, MO

J Biol Chem 2003
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Orthologous Events
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Bos taurus)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Mus musculus)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Rattus norvegicus)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Sus scrofa)
Authored
Garapati, P V  (2010-08-02)
Reviewed
Akira, S  (2010-10-30)
Kawai, T  (2010-10-30)
Created
Garapati, P V  (2010-11-18)
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