Translocation of phosphorylated IRF3,IRF7 dimers into nucleus

Stable Identifier
R-HSA-1028816
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Phosphorylated IRF dimers after dimerization translocates into the nucleus and associate with general coactivators like CBP/p300 and bind to type-I IFN promoter region.

Literature References
PubMed ID Title Journal Year
12604599 Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators

Yang, H, Lin, CH, Ma, G, Baffi, MO, Wathelet, MG

J Biol Chem 2003
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created