Expression of interferon-beta

Stable Identifier
R-HSA-1028812
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
extracellular region
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Summation

The IFN-beta genes are transcribed and translated yielding IFNB proteins which are secreted. This process is positively regulated by IRF3:CBP/p300 transcription factor complex.

Literature References
PubMed ID Title Journal Year
20627800 Regulation of immune cell homeostasis by type I interferons

Mattei, F, Schiavoni, G, Tough, DF

Cytokine Growth Factor Rev 2010
11244049 IRF family of transcription factors as regulators of host defense

Taniguchi, T, Ogasawara, K, Takaoka, A, Tanaka, N

Annu Rev Immunol 2001
Participants
Input
Output
Participant Of
hasEvent
This entity is regulated by
Positive Regulation
Authored
Garapati, P V  (2010-08-02)
Reviewed
Kawai, T  (2010-10-30)
Akira, S  (2010-10-30)