Reactome | ZNF224 [nucleoplasm]

ZNF224 [nucleoplasm]

Stable Identifier

R-HSA-1027352

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger protein 224, ZN224_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NZL3 ZNF224

Gene Names

ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27

Chain

chain:1-707

Reference Genes

BioGPS Gene:7767 ZNF224

COSMIC (genes):ZNF224 ZNF224

COSMIC (genes):ZNF233 ZNF224

CTD Gene:7767 ZNF224

dbSNP Gene:7767 ZNF224

ENSEMBL:ENSG00000267680 ZNF224

HGNC:13017 ZNF224

KEGG:hsa:7767 ZNF224

Monarch:7767 ZNF224

NCBI Gene:7767 ZNF224

OMIM:194555 ZNF224

UCSC:Q9NZL3 ZNF224

Reference Transcript

Other Identifiers

11731741_at

16862918

216983_3p_s_at

216983_PM_s_at

216983_s_at

220019_PM_s_at

220019_s_at

229123_PM_at

229123_at

244462_PM_at

244462_at

3835324

3835419

3835420

3835421

3835422

3835423

3835424

3835425

3835426

3835427

3835429

3835430

3835431

3835432

3835433

3835434

3835435

3835436

3835437

3835444

49331_at

55812_at

7767

8029377

A_14_P121528

A_14_P129375

A_23_P10885

A_24_P36285

A_24_P941309

GE54952

GO:0000122

GO:0000978

GO:0001227

GO:0001228

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0017053

GO:0031965

GO:0043226

GO:0043565

GO:0045892

GO:0045944

GO:0046872

GO:0140110

HMNXSV003015263

Hs.122605.1.S1_3p_x_at

Hs.131708.0.A1_3p_at

Hs.293350.0.A1_3p_at

ILMN_1661293

PH_hs_0032462

TC19000616.hg

g5031614_3p_s_at

Participates

as a candidate of

Inferred To

Homologues of ZNF224 [nucleoplasm] (Danio rerio)

Homologues of ZNF224 [nucleoplasm] (Drosophila melanogaster)

ZNF224 [nucleoplasm] (Danio rerio)

ZNF224 [nucleoplasm] (Drosophila melanogaster)

mld [nucleoplasm] (Drosophila melanogaster)

Dmel\CG18011 [nucleoplasm] (Drosophila melanogaster)

si:ch211-119o8.6 [nucleoplasm] (Danio rerio)

drll.3 [nucleoplasm] (Danio rerio)

znf-236 [nucleoplasm] (Caenorhabditis elegans)

znf990 [nucleoplasm] (Danio rerio)

Cross References

OpenTargets

ENSG00000267680

ENSEMBL

ENSP00000508532, ENSP00000509045, ENST00000684943, ENSP00000337368, ENST00000336976, ENST00000693561

HPA

ENSG00000267680-ZNF224

PRO

Q9NZL3

Pharos - Targets

Q9NZL3

PDB

2ENA, 2YSP, 2ELZ, 2ELY, 2EM7, 2EM8, 2EM9, 2EM6, 2EN8, 2YTH, 2EQ4, 2EOQ, 2EM0, 2ENC, 2EN1, 2EOR

HMDB Protein

HMDBP10905

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NW38 FANCL	2	FANCL [nucleoplasm] (R-HSA-419520) FANCL [cytosol] (R-HSA-420789)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.553	2
UniProt:Q9UM47 NOTCH3	20	Ub-NICD3 [cytosol] (R-HSA-9021546) Ub-NEXT3 [plasma membrane] (R-HSA-9021545) p-Y-NICD3 [cytosol] (R-HSA-9018581) Glc,GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane] (R-HSA-1911429) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane] (R-HSA-1911419) NOTCH3(1572-2321) [Golgi membrane] (R-HSA-156995) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [Golgi membrane] (R-HSA-1983672) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region] (R-HSA-1983675) NOTCH3(1572-2321) [plasma membrane] (R-HSA-157231) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [Golgi membrane] (R-HSA-1472871) 14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane] (R-HSA-1467307) 10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane] (R-HSA-1467382) Pre-NOTCH3 [endoplasmic reticulum membrane] (R-HSA-157102) NICD3 [nucleoplasm] (R-HSA-157928) NICD3 [cytosol] (R-HSA-157647) NEXT3 [plasma membrane] (R-HSA-157203) NOTCH3(1629-1661) [plasma membrane] (R-HSA-157657) NOTCH3(40-1628) [extracellular region] (R-HSA-157639) FRINGE-modified NOTCH3 Extracellular fragment (NECD3) [Golgi membrane] (R-HSA-1911522) FRINGE-modified NOTCH3 Extracellular Fragment (NECD3) [plasma membrane] (R-HSA-1911517)	0.527	2
UniProt:Q92673 SORL1	2	SORL1 [endosome membrane] (R-HSA-8871475) SORL1 [Golgi membrane] (R-HSA-8871510)	0.527	2
UniProt:P98164 LRP2	2	LRP2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869099) LRP2 [plasma membrane] (R-HSA-350083)	0.527	2