Reactome | LMAN1 [ER to Golgi transport vesicle membrane]

LMAN1 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-HSA-1017222

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ER to Golgi transport vesicle membrane

Synonyms

Protein ERGIC-53, LMAN1_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        CSNK1D phosphorylates SEC23 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        Nucleotide exchange on RAB1 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi (Homo sapiens)
        
        LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - CSNK1D phosphorylates SEC23 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - Nucleotide exchange on RAB1 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
      - Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 hexamer [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
        
        LMAN1 [ER to Golgi transport vesicle membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P49257 LMAN1

Gene Names

LMAN1, ERGIC53, F5F8D

Chain

signal peptide:1-30, chain:31-510

Reference Genes

BioGPS Gene:3998 LMAN1

COSMIC (genes):LMAN1 LMAN1

CTD Gene:3998 LMAN1

dbSNP Gene:3998 LMAN1

ENSEMBL:ENSG00000074695 LMAN1

HGNC:6631 LMAN1

KEGG:hsa:3998 LMAN1

Monarch:3998 LMAN1

NCBI Gene:3998 LMAN1

OMIM:601567 LMAN1

UCSC:P49257 LMAN1

Reference Transcript

RefSeq:NM_005570.3 LMAN1

Other Identifiers

11724210_at

11724211_a_at

11724212_at

11724213_at

11747181_a_at

11760808_at

16855578

203293_PM_s_at

203293_s_at

203294_PM_s_at

203294_s_at

224629_PM_at

224629_at

34734_at

3810473

3810474

3810475

3810476

3810477

3810478

3810479

3810480

3810481

3810483

3810484

3810487

3810488

3810489

3810490

3810492

3810494

3810495

3810496

3810497

3810498

3810499

3810500

3810501

3998

64263_s_at

65907_r_at

8023561

A_23_P78342

A_24_P159702

GE79723

GE85846

GO:0000139

GO:0005515

GO:0005537

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006457

GO:0006888

GO:0007029

GO:0007030

GO:0007596

GO:0010638

GO:0012507

GO:0015031

GO:0016020

GO:0016192

GO:0030017

GO:0030134

GO:0030246

GO:0030312

GO:0031012

GO:0031410

GO:0033116

GO:0043226

GO:0046872

GO:0051082

GO:0062023

GO:0070062

GO:1903215

HMNXSV003027212

Hs.5822.0.S1_3p_at

ILMN_1715814

PH_hs_0025520

TC18000547.hg

U09716_s_at

X71661_at

g10862689_3p_s_at

g606827_3p_a_at

Participates

as a component of

Other forms of this molecule

LMAN1 [Golgi membrane]

LMAN1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

LMAN1 [endoplasmic reticulum membrane]

Inferred To

cplx3 [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)

ile-1 [ER to Golgi transport vesicle membrane] (Caenorhabditis elegans)

LMAN1 [ER to Golgi transport vesicle membrane] (Bos taurus)

LMAN1 [ER to Golgi transport vesicle membrane] (Canis familiaris)

LMAN1 [ER to Golgi transport vesicle membrane] (Dictyostelium discoideum)

LMAN1 [ER to Golgi transport vesicle membrane] (Gallus gallus)

LMAN1 [ER to Golgi transport vesicle membrane] (Mus musculus)

LMAN1 [ER to Golgi transport vesicle membrane] (Rattus norvegicus)

LMAN1 [ER to Golgi transport vesicle membrane] (Sus scrofa)

ergic53 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000251047, ENST00000251047

OpenTargets

ENSG00000074695

HPA

ENSG00000074695-LMAN1

PRO

P49257

Pharos - Targets

P49257

GlyGen

P49257

Orphanet

LMAN1

PDB

3WHT, 4YGE, 3A4U, 3WHU, 3WNX, 3LCP, 4YGB, 4GKX, 8JPG, 4YGD, 4YGC, 4GKY, 8JP5, 8JP6, 8JP8, 8JP4, 8JP7, 8JP9

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	3

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