Reactome | IRF2 [cytosol]

IRF2 [cytosol]

Stable Identifier

R-HSA-1015681

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Interferon regulatory factor 2, IRF2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P14316 IRF2

Gene Names

IRF2

Chain

chain:1-349

Reference Genes

BioGPS Gene:3660 IRF2

COSMIC (genes):IRF2 IRF2

CTD Gene:3660 IRF2

dbSNP Gene:3660 IRF2

ENSEMBL:ENSG00000168310 IRF2

HGNC:6117 IRF2

KEGG:hsa:3660 IRF2

Monarch:3660 IRF2

NCBI Gene:3660 IRF2

OMIM:147576 IRF2

UCSC:P14316 IRF2

Reference Transcript

RefSeq:NM_002199.3 IRF2

Other Identifiers

11754330_a_at

1219_at

1220_g_at

16981979

16981997

203275_PM_at

203275_at

2796383

2796385

2796386

2796387

2796388

2796389

2796390

2796394

2796396

2796399

2796402

2796403

2796411

2796412

2796413

2796414

2796419

2796420

2796427

2796428

2796430

2796439

3660

42723_at

8103911

A_21_P0003815

A_23_P136478

GE58275

GO:0000122

GO:0000785

GO:0000976

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0002376

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0005925

GO:0006355

GO:0006357

GO:0008283

GO:0043226

GO:0045944

GO:0051607

GO:0098542

GO:0140110

GO:1990837

HMNXSV003010199

HMNXSV003020054

ILMN_1765547

ILMN_2090607

PH_hs_0004779

TC04001805.hg

TC04002878.hg

X15949_at

g4755144_3p_at

g4755144_3p_x_at

p22408

Participates

as a member of

IRF 1-9 [cytosol] (Homo sapiens)

Other forms of this molecule

IRF2 [nucleoplasm]

Cross References

RefSeq

NP_002190.2

OpenTargets

ENSG00000168310

ENSEMBL

ENSP00000512954, ENSP00000512878, ENST00000696849, ENSP00000424552, ENSP00000512929, ENSP00000512925, ENSP00000512927, ENST00000696843, ENST00000696848, ENST00000696840, ENST00000696845, ENST00000393593, ENST00000696846, ENST00000696841, ENSP00000512924, ENSP00000512923, ENSP00000512922, ENSP00000512920, ENSG00000168310, ENSP00000512918, ENST00000696851, ENSP00000377218, ENST00000504340, ENST00000510814, ENST00000696853

HPA

ENSG00000168310-IRF2

GeneCards

IRF2

PRO

P14316

Pharos - Targets

P14316

GlyGen

P14316

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01167 FOXK2	1	FOXK2 [nucleoplasm] (R-HSA-5689655)	0.773	5
UniProt:Q9H1B7 I2BPL			0.725	4
UniProt:Q8IU81 I2BP1			0.725	4
UniProt:P85037 FOXK1	1	FOXK1 [nucleoplasm] (R-HSA-5689673)	0.708	4
UniProt:Q9Y5Z7 HCFC2	1	HCFC2 [nucleoplasm] (R-HSA-9821232)	0.643	3
UniProt:Q7Z5L9 I2BP2			0.643	3
UniProt:Q5VWN6 TASO2			0.623	3
UniProt:P51610 HCFC1	2	HCFC1 [nucleoplasm] (R-HSA-1592209) K48polyUb,K63polyUb-HCFC1 [nucleoplasm] (R-HSA-5690821)	0.527	2
UniProt:P25774 CTSS	6	CTSS [endolysosome lumen] (R-HSA-1679012) CTSS [ficolin-1-rich granule lumen] (R-HSA-6801274) CTSS [extracellular region] (R-HSA-6801535) CTSS [tertiary granule lumen] (R-HSA-6801308) CTSS [early endosome lumen] (R-HSA-1236751) CTSS [lysosomal lumen] (R-HSA-1181234)	0.527	2
UniProt:O95352 ATG7	14	ATG7 [cytosol] (R-HSA-947867) CysO572-ATG7 [cytosol] (R-HSA-5683584) CysO572-ATG7-GARABAPL3 [cytosol] (R-HSA-9820420) CysO572-ATG7-MAP1LC3A [cytosol] (R-HSA-9820421) CysO572-ATG7-MAP1LC3C [cytosol] (R-HSA-9820407) CysO572-ATG7-GARABAPL1 [cytosol] (R-HSA-9820406) CysO572-ATG7-GARABAP [cytosol] (R-HSA-9820417) CysO572-ATG7-GARABAPL2 [cytosol] (R-HSA-9820413) CysO572-ATG7-MAP1LC3B [cytosol] (R-HSA-9820410) ATG7(1-693)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802517) ATG7(1-693)-BRAF(381-766) fusion [cytosol] (R-HSA-6802272) ATG7 [ficolin-1-rich granule lumen] (R-HSA-6801293) ATG7 [extracellular region] (R-HSA-6806451) ATG7 [secretory granule lumen] (R-HSA-6801316)	0.499	2
UniProt:P16298 PPP3CB	2	PPP3CB [nucleoplasm] (R-HSA-2685624) PPP3CB [cytosol] (R-HSA-2025869)	0.499	2

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