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OAS3 [cytosol]
Stable Identifier
R-HSA-1015672
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
2'-5'-oligoadenylate synthase 3, OAS3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
OAS antiviral response (Homo sapiens)
OAS3 binds viral dsRNA (Homo sapiens)
OAS3 [cytosol] (Homo sapiens)
OAS3:OAS3 ligand [cytosol] (Homo sapiens)
OAS3 [cytosol] (Homo sapiens)
OAS3 produces oligoadenylates (Homo sapiens)
OAS3:OAS3 ligand [cytosol] (Homo sapiens)
OAS3 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
OAS proteins [cytosol] (Homo sapiens)
OAS3 [cytosol] (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Expression of IFNG-stimulated genes (Homo sapiens)
OAS proteins [cytosol] (Homo sapiens)
OAS3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6K5 OAS3
Gene Names
OAS3, P/OKcl.4
Chain
chain:1-1087
Reference Genes
BioGPS Gene:4940 OAS3
COSMIC (genes):OAS3 OAS3
CTD Gene:4940 OAS3
dbSNP Gene:4940 OAS3
ENSEMBL:ENSG00000111331.14 OAS3
HGNC:8088 OAS3
KEGG Gene (Homo sapiens):4940 OAS3
Monarch:4940 OAS3
NCBI Gene:4940 OAS3
OMIM:603351 OAS3
UCSC:Q9Y6K5 OAS3
Reference Transcript
RefSeq:NM_006187.3 OAS3
Other Identifiers
11723698_a_at
11723699_s_at
11723700_at
16757347
218400_PM_at
218400_at
3432468
3432469
3432470
3432471
3432472
3432476
3432477
3432479
3432481
3432483
3432484
3432485
3432486
3432487
3432488
3432489
3432490
3432491
3432492
3432493
3432494
3432495
3432497
3432498
3432499
3432500
3432501
3432504
3432505
3432507
3432508
3432509
3432510
3432511
3432513
4940
64450_at
7958895
A_14_P107746
A_23_P47955
A_24_P335305
A_33_P3402489
GE81606
GO:0000166
GO:0001730
GO:0002376
GO:0003723
GO:0003725
GO:0003824
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006139
GO:0009615
GO:0016020
GO:0016740
GO:0016779
GO:0023052
GO:0032728
GO:0032760
GO:0035395
GO:0039529
GO:0039530
GO:0042742
GO:0043226
GO:0043231
GO:0045071
GO:0045087
GO:0046872
GO:0051607
GO:0060339
GO:0060700
GO:0071639
GO:0071650
GO:0071659
GO:0098542
GO:2000342
HMNXSV003003467
ILMN_1745397
ILMN_2184262
PH_hs_0022428
TC12000885.hg
g5453823_3p_at
Participates
as an input of
OAS3 binds viral dsRNA (Homo sapiens)
as a component of
OAS3:OAS3 ligand [cytosol] (Homo sapiens)
as a member of
OAS proteins [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_006178.2
OpenTargets
ENSG00000111331
GeneCards
Q9Y6K5
HPA
ENSG00000111331-OAS3
Ensembl
ENSG00000111331
,
ENSP00000228928
,
ENST00000228928
PRO
Q9Y6K5
Pharos - Targets
Q9Y6K5
HMDB Protein
HMDBP08494
PDB
4S3N
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BZE4 GTPB4
0.527
2
UniProt:Q969S3 ZN622
0.527
2
UniProt:Q8IY81 FTSJ3
1
FTSJ3 [nucleoplasm]
(R-HSA-6791507)
0.499
2
UniProt:P56537 IF6
0.499
2
UniProt:Q7Z434 MAVS
2
MAVS [mitochondrial outer membrane]
(R-HSA-913730)
K48polyUb-MAVS [mitochondrial outer membrane]
(R-HSA-983463)
0.499
2
UniProt:Q7L2E3 DHX30
0.499
2
UniProt:Q12894 IFRD2
0.499
2
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