Association of GABA B receptor with G protein beta-gamma subunits

Stable Identifier
R-HSA-1013013
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
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Activation of GABA B receptors by GABA stimulates Gi/o proteins releasing the G beta gamma subunit that binds to voltage dependent Ca2+ channels.

Literature References
PubMed ID Title Journal Year
20453851 Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling

Xie, K, Allen, KL, Kourrich, S, Colón-Saez, J, Thomas, MJ, Wickman, K, Martemyanov, KA

Nat Neurosci 2010
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
G protein-coupled GABA receptor activity of GABAB receptor:GABA [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created