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DOCK10 [cytosol]
Stable Identifier
R-HSA-1012998
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Dedicator of cytokinesis protein 10, DOC10_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
DOCKs bind to RhoGEFs (Homo sapiens)
DOCK-GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
DOCK-GEFs:RAC1, CDC42 [cytosol] (Homo sapiens)
DOCK-GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 GEFs activate RAC2 (Homo sapiens)
RAC2 GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GEFs activate RAC3 (Homo sapiens)
RAC3 GEFs [cytosol] (Homo sapiens)
DOCK10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96BY6 DOCK10
Gene Names
DOCK10, KIAA0694, ZIZ3
Chain
chain:1-2186
Reference Genes
BioGPS Gene:55619 DOCK10
COSMIC (genes):DOCK10 DOCK10
CTD Gene:55619 DOCK10
dbSNP Gene:55619 DOCK10
ENSEMBL:ENSG00000135905.20 DOCK10
HGNC:23479 DOCK10
KEGG Gene (Homo sapiens):55619 DOCK10
Monarch:55619 DOCK10
NCBI Gene:55619 DOCK10
OMIM:611518 DOCK10
UCSC:Q96BY6 DOCK10
Reference Transcript
RefSeq:NM_001290263.1 DOCK10
RefSeq:NM_014689.2 DOCK10
Other Identifiers
0002970600
0101770373
0103850008
11723863_a_at
11746710_a_at
11758539_s_at
16909081
219279_3p_at
219279_PM_at
219279_at
2601651
2601652
2601653
2601660
2601661
2601662
2601665
2601666
2601667
2601670
2601671
2601672
2601673
2601674
2601675
2601677
2601678
2601679
2601680
2601681
2601682
2601683
2601684
2601686
2601687
2601688
2601689
2601690
2601692
2601694
2601695
2601697
2601699
2601700
2601702
2601704
2601705
2601706
2601708
2601709
2601710
2601711
2601716
2601717
2601718
2601719
2601722
2601723
2601730
2601731
2601732
2601734
2601735
2601736
2601737
2601738
2601739
2601746
2601747
2601748
2601750
2601753
2601762
2601766
2601767
2601768
2601790
2601791
2601792
31766_s_at
55619
60789_at
8059413
GE55408
GO:0001782
GO:0002315
GO:0002376
GO:0003674
GO:0005085
GO:0005515
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0007264
GO:0016020
GO:0023052
GO:0030154
GO:0030334
GO:0034330
GO:0042995
GO:0043197
GO:0043226
GO:0043547
GO:0045202
GO:0048856
GO:0048870
GO:0060997
GO:0070062
GO:0098772
HMNXSV003008506
HMNXSV003012969
ILMN_1702301
PH_hs_0001821
TC02002827.hg
g8923209_3p_at
g8923209_3p_x_at
Participates
as a candidate of
CDC42 GEFs [cytosol] (Homo sapiens)
RAC2 GEFs [cytosol] (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
RAC3 GEFs [cytosol] (Homo sapiens)
DOCK-GEFs [cytosol] (Homo sapiens)
Inferred To
Dock10 [cytosol]
(Mus musculus)
Ziz [cytosol]
(Drosophila melanogaster)
Homologues of DOCK10 [cytosol]
(Dictyostelium discoideum)
DOCK10 [cytosol]
(Bos taurus)
DOCK10 [cytosol]
(Caenorhabditis elegans)
DOCK10 [cytosol]
(Canis familiaris)
DOCK10 [cytosol]
(Danio rerio)
DOCK10 [cytosol]
(Dictyostelium discoideum)
DOCK10 [cytosol]
(Gallus gallus)
DOCK10 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001277192.1
,
NP_055504.2
OpenTargets
ENSG00000135905
HPA
ENSG00000135905-DOCK10
GeneCards
Q96BY6
Ensembl
ENST00000258390
,
ENSG00000135905
,
ENSP00000258390
,
ENST00000409592
,
ENSP00000386694
PRO
Q96BY6
Pharos - Targets
Q96BY6
HMDB Protein
HMDBP08350
PDB
6TKY
,
6TM1
,
6TKZ
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