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Expression of globin genes under control of the beta globin control region
Stable Identifier
R-HSA-1008220
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
Expression of globin genes under control of the beta globin control region (Homo sapiens)
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The human beta-globin locus consists of five genes encoding the beta globin gene but also delta, gamma-A, gamma-G and epsilon globin. All of these genes are controlled by the beta globin locus control region.
Literature References
PubMed ID
Title
Journal
Year
11895428
The human beta-globin locus control region
Levings, PP
,
Bungert, J
Eur J Biochem
2002
Participants
Input
Globin genes [nucleoplasm]
(Homo sapiens)
Output
HBB [cytosol]
(Homo sapiens)
HBD [cytosol]
(Homo sapiens)
HBE1 [cytosol]
(Homo sapiens)
HBG1 [cytosol]
(Homo sapiens)
HBG2 [cytosol]
(Homo sapiens)
Participates
as an event of
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
This event is regulated
Positively by
Regulator
NF-E2:Promoter region of beta-globin [nucleoplasm]
(Homo sapiens)
Authored
Ouwehand, WH (2010-11-12)
Reviewed
Akkerman, JW (2010-10-29)
Created
Jupe, S (2010-11-10)
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