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What is Reactome ?
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HCV dsRNA intermediate form [endosome lumen]
Stable Identifier
R-HCV-8982462
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Hepatitis C Virus
Compartment
endosome lumen
Synonyms
HCV dsRNA replicative intermediate form, viral double-stranded RNA
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of Immune System (Homo sapiens)
Diseases associated with the TLR signaling cascade (Homo sapiens)
TICAM1 deficiency - HSE (Homo sapiens)
TICAM1 deficiency blocks TLR3 pathway (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TRAF3 deficiency - HSE (Homo sapiens)
Defective TRAF3 does not transmit the signal (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
RIP-mediated NFkB activation via ZBP1 (Homo sapiens)
RIP1 facilitates IKK complex phosphorylation (Homo sapiens)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
SARM binds viral dsRNA:TLR3:TICAM1 (Homo sapiens)
SARM:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TICAM1, RIP1-mediated IKK complex recruitment (Homo sapiens)
IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex (Homo sapiens)
activated TLR3:TICAM1:K63pUb-RIP1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:K63pUb-RIP1:CHUK:IKBKB:IKBKG [endosome membrane] (Homo sapiens)
activated TLR3:TICAM1:K63pUb-RIP1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Homo sapiens)
activated TLR3:TICAM1:K63pUb-RIP1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Viral dsRNA:TLR3:TRIF complex recruits RIP1 (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TICAM1,TRAF6-dependent induction of TAK1 complex (Homo sapiens)
Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Activation of recruited TAK1 within the activated TLR3 complex (Homo sapiens)
viral dsRNA:TLR3:TRIF:pUb-TRAF6:TAB1:TAB2,TAB3:free polyUb: p-TAK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TRIF:TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Phosphorylated TAK1 dissociates from the TLR3 receptor complex (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TRIF:pUb-TRAF6:TAB1:TAB2,TAB3:free polyUb: p-TAK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:K63pUb-TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Viral dsRNA:TLR3:TICAM1 complex recruits TRAF6 (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TRIF:TRAF6 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TICAM1-dependent activation of IRF3/IRF7 (Homo sapiens)
Auto-ubiquitination of TRAF3 within activated TLR3 complex (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
IKKε (IKBKE) binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 (Homo sapiens)
IKBKE:K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
IKKε (IKBKE) is phosphorylated within the activated TLR3 complex (Homo sapiens)
IKBKE:K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
p-S172-IKBKE:K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation (Homo sapiens)
IKKε (IKBKE) is ubiquitinated within the activated TLR3 complex (Homo sapiens)
IKBKE:K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
K63pUb-IKBKE:K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
OPTN binds TBK1 within the activated TLR3 complex (Homo sapiens)
OPTN:TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 (Homo sapiens)
K63polyUb-TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR3 (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TANK:K63-poly-Ub-TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TICAM1:TLR3:viral dsRNA (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TANK:K63-poly-Ub-TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1 binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1 is phosphorylated within the activated TLR3 complex (Homo sapiens)
OPTN:TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
p-S172-TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [endosome membrane] (Homo sapiens)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TLR3:viral dsRNA [endosome membrane] (Homo sapiens)
K63polyUb-TRAF3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TRAF3 binds to TRIF:activated TLR3 complex (Homo sapiens)
TRAF3:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TLR3-mediated TICAM1-dependent programmed cell death (Homo sapiens)
Caspase-8 processing within TLR3 complex (Homo sapiens)
activated TLR3:TRIF:RIP1:FADD [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis (Homo sapiens)
RIP3:TICAM1:activated TLR3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:RIPK1:RIPK3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:RIPK3 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TICAM1:activated TLR3 complexes [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
TLR3-induced ripoptosome assembly (Homo sapiens)
activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane] (Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Viral dsRNA binds the Toll-Like Receptor 3 (TLR3) (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Viral dsRNA:TLR3 recruits TRIF (TICAM1) (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
viral dsRNA:TLR3:TICAM1 [endosome membrane] (Homo sapiens)
viral dsRNA :TLR3 [endosome membrane] (Homo sapiens)
TLR3 ligand [endosome lumen] (Hepatitis B virus)
HCV dsRNA intermediate form [endosome lumen] (Hepatitis C Virus)
Participates
as a member of
TLR3 ligand [endosome lumen] (Hepatitis B virus)
Disease
Name
Identifier
Synonyms
viral infectious disease
DOID:934
Viral disease, virus infection, virus infection
Cross References
ChEBI
67208
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