Reactome | BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane]

BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-GGA-983044-17

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor, Q95601

Locations in the PathwayBrowser

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Immune System (Gallus gallus)

- Adaptive Immune System (Gallus gallus)
  - Class I MHC mediated antigen processing & presentation (Gallus gallus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Gallus gallus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
      - Budding of COPII coated vesicle (Gallus gallus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Gallus gallus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
      - Loading of antigenic peptides on to class I MHC (Gallus gallus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Gallus gallus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Gallus gallus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Gallus gallus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Gallus gallus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
      - Transport of MHC heterotrimer to ER exit site (Gallus gallus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)
        
        BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q95601

Gene Names

BFIV21

Reference Genes

BioGPS Gene:425389 BFIV21

CTD Gene:425389 BFIV21

ENSEMBL:ENSGALG00000041380

KEGG Gene (Gallus gallus):425389 BFIV21

Monarch:425389 BFIV21

NCBI Gene:425389 BFIV21

Reference Transcript

RefSeq:NM_001031338.1 BFIV21

Other Identifiers

425389

GO:0003674

GO:0005575

GO:0005576

GO:0005615

GO:0005886

GO:0009897

GO:0016020

GO:0016021

GO:0043167

GO:0046872

GT_A_87_P058651

GT_A_87_P060206

GT_A_87_P128773

GT_A_87_P130067

Gga.4973.1.S1_x_at

Gga.4973.3.S1_x_at

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Gallus gallus)

Other forms of this molecule

BFIV21 [extracellular region]

BFIV21 [plasma membrane]

BFIV21 [secretory granule membrane]

BFIV21 [azurophil granule membrane]

BFIV21 [ER to Golgi transport vesicle membrane]

BFIV21 [Golgi membrane]

BFIV21 [phagocytic vesicle membrane]

BFIV21 [plasma membrane]

BFIV21 [integral component of lumenal side of endoplasmic reticulum membrane]

BFIV21 [plasma membrane]

BFIV21 [early endosome membrane]

BFIV21 [plasma membrane]

BFIV21 [recycling endosome membrane]

BFIV21 [phagocytic vesicle membrane]

Inferred From

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001026509.1

Ensembl

ENSGALP00000043493, ENSGALT00000079478, ENSGALG00000041380

PDB

5AD0, 3BEV, 4D0B, 2YEZ, 5ACZ, 4D0C, 3BEW, 4CVZ

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