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TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane]
Stable Identifier
R-GGA-9796354
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Gallus gallus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Gallus gallus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Gallus gallus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MIB2 [cytosol]
(Gallus gallus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane]
(Gallus gallus)
Ub:UBE2D1 [cytosol]
(Gallus gallus)
Participates
as an input of
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Gallus gallus)
as an output of
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Gallus gallus)
Inferred From
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane]
(Homo sapiens)
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