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p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm]
Stable Identifier
R-GGA-9754128
Type
Set [DefinedSet]
Species
Gallus gallus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
Mitotic G1 phase and G1/S transition (Gallus gallus)
G1 Phase (Gallus gallus)
Cyclin D associated events in G1 (Gallus gallus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Gallus gallus)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Gallus gallus)
Drug-mediated inhibition of CDK4/CDK6 activity (Gallus gallus)
CDK6 inhibitors bind CDK6 (Gallus gallus)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Gallus gallus)
Participants
members
p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm]
(Gallus gallus)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm]
(Gallus gallus)
p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm]
(Gallus gallus)
Participates
as an output of
CDK6 inhibitors bind CDK6 (Gallus gallus)
This entity regulates
Negatively
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes
(Gallus gallus)
Inferred From
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm]
(Homo sapiens)
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