Reactome | NMUR1 [plasma membrane]

NMUR1 [plasma membrane]

Stable Identifier

R-GGA-964790

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

E1BWP2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
    - G alpha (q) signalling events (Gallus gallus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Peptide ligand-binding receptors (Gallus gallus)
        
        Neuromedin-U receptors bind neuromedins U, S (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2:NMU [plasma membrane] (Gallus gallus)
        
        NMUR1,NMUR2 [plasma membrane] (Gallus gallus)
        
        NMUR1 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BWP2

Reference Genes

BioGPS Gene:429150

ENSEMBL:ENSGALG00000007714

KEGG Gene (Gallus gallus):429150

Monarch:429150

NCBI Gene:429150

Reference Transcript

Participates

as a member of

NMUR1,NMUR2 [plasma membrane] (Gallus gallus)

Inferred From

NMUR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001305365.1, XP_015146979.1, XP_015146980.1, XP_004943428.1

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