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holoTF:TFRC dimer [plasma membrane]
Stable Identifier
R-GGA-917834
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Gallus gallus)
Iron uptake and transport (Gallus gallus)
Transferrin endocytosis and recycling (Gallus gallus)
TFRC dimer binds 2xholoTF (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Clathrin-mediated endocytosis (Gallus gallus)
BAR domain proteins recruit dynamin (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Cargo recognition for clathrin-mediated endocytosis (Gallus gallus)
AP-2 directly binds some endocytic cargo (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Clathrin recruits PIK3C2A (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
SNX9 recruits components of the actin polymerizing machinery (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Gallus gallus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Gallus gallus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Gallus gallus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Gallus gallus)
CLASP proteins:cargo [plasma membrane] (Gallus gallus)
AP-2:cargo [plasma membrane] (Gallus gallus)
AP-2 cargo [plasma membrane] (Gallus gallus)
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
holoTF:TFRC dimer [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
holoTF [extracellular region]
(Gallus gallus)
TFRC dimer [plasma membrane]
(Gallus gallus)
Participates
as a member of
AP-2 YXXPhi cargo [plasma membrane] (Gallus gallus)
as an output of
TFRC dimer binds 2xholoTF (Gallus gallus)
as an input of
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Gallus gallus)
Inferred From
holoTF:TFRC dimer [plasma membrane]
(Homo sapiens)
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