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What is Reactome ?
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Digital Preservation
Contact us
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Table of Contents
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IL5 homodimer [extracellular region]
Stable Identifier
R-GGA-913383
Type
Complex
Species
Gallus gallus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-2 family signaling (Gallus gallus)
Interleukin receptor SHC signaling (Gallus gallus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC recruits GRB2:SOS1 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC1 recruits SHIP (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Gallus gallus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
14-3-3 zeta binding allows recruitment of PI3K (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Activation of STAT5a/b by JAK2 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor SHC signaling (Gallus gallus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC recruits GRB2:SOS1 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Phosphorylated SHC1 recruits SHIP (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Gallus gallus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin-5 is a homodimer (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin-5 receptor alpha subunit binds Interleukin-5 (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
JAK2 is phosphorylated, activated (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
SHP1 and SHP2 bind the common beta chain (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
STAT5 is recruited by JAK2 (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
The receptor is activated (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Tyrosine kinases phosphorylate the receptor (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
p-S585-IL3RB binds 14-3-3 proteins (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
p-STAT5 dissociates from the receptor complex (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
Signal Transduction (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Gallus gallus)
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
IL5 homodimer [extracellular region] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
IL5 [extracellular region]
(Gallus gallus)
Participates
as an input of
Interleukin-5 receptor alpha subunit binds Interleukin-5 (Gallus gallus)
as an output of
Interleukin-5 is a homodimer (Gallus gallus)
as a component of
IL5 homodimer:IL5RA [plasma membrane] (Gallus gallus)
Inferred From
IL5 homodimer [extracellular region]
(Homo sapiens)
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