Reactome | CAPZA3 [cytosol]

CAPZA3 [cytosol]

Stable Identifier

R-GGA-8982306

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

CAPZA3, E1BUP3

Locations in the PathwayBrowser

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Cellular responses to stimuli (Gallus gallus)

- Cellular responses to stress (Gallus gallus)
  - HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Gallus gallus)
    - HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Gallus gallus)
      - Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)

Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Asparagine N-linked glycosylation (Gallus gallus)
    - Transport to the Golgi and subsequent modification (Gallus gallus)
      - ER to Golgi Anterograde Transport (Gallus gallus)
        
        COPI-mediated anterograde transport (Gallus gallus)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)

Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - ER to Golgi Anterograde Transport (Gallus gallus)
    - COPI-mediated anterograde transport (Gallus gallus)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Gallus gallus)
    - Golgi-to-ER retrograde transport (Gallus gallus)
      - COPI-independent Golgi-to-ER retrograde traffic (Gallus gallus)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Gallus gallus)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Gallus gallus)
        
        Dynein:Dynactin:microtubule [cytosol] (Gallus gallus)
        
        Dynactin [cytosol] (Gallus gallus)
        
        Dynactin rod [cytosol] (Gallus gallus)
        
        CAPZ [cytosol] (Gallus gallus)
        
        CAPZA3:CAPZB [cytosol] (Gallus gallus)
        
        CAPZA3 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BUP3

Gene Names

CAPZA3

Reference Genes

BioGPS Gene:427929 CAPZA3

ENSEMBL:ENSGALG00000013125

ENSEMBL:ENSGALG00010014904.1 CAPZA3

KEGG Gene (Gallus gallus):427929 CAPZA3

Monarch:427929 CAPZA3

NCBI Gene:427929 CAPZA3

Reference Transcript

RefSeq:NM_001278118.1 CAPZA3

Other Identifiers

427929

GO:0003779

GO:0005856

GO:0007010

GO:0008092

GO:0008290

GO:0016020

GO:0030036

GO:0030863

GO:0043226

GO:0051015

GO:0051016

GO:0051693

GO:0065003

GT_A_87_P157273

GgaAffx.8339.1.S1_at

Participates

as a component of

CAPZA3:CAPZB [cytosol] (Gallus gallus)

Inferred From

CAPZA3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001265047.1

OpenTargets

ENSG00000177938

Ensembl

ENSGALT00010035860, ENSGALP00010020798, ENSGALG00010014904

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