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phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
Stable Identifier
R-GGA-8874613
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
Q00944
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by MET (Gallus gallus)
MET promotes cell motility (Gallus gallus)
MET activates PTK2 signaling (Gallus gallus)
SRC phosphorylates PTK2 (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Gallus gallus)
phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q00944
Reference Genes
ENSEMBL:ENSGALG00000031741
KEGG Gene (Gallus gallus):396416
Reference Transcript
RefSeq:NM_205435.1
Participates
as a component of
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Gallus gallus)
Other forms of this molecule
phospho-pY-PTK2 [cytosol]
phospho-p-Y194,Y397-PTK2 [cytosol]
phospho-p-5Y-PTK2 [cytosol]
phospho-p-5Y,S732-PTK2 [cytosol]
phospho-p-6Y,S732-PTK2 [cytosol]
PTK2(773-1052) [cytosol]
PTK2(1-772) [cytosol]
PTK2 [cytosol]
phospho-p-Y397-PTK2 [cytosol]
phospho-p-6Y-PTK2 [cytosol]
Inferred From
p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 397 (in Homo sapiens)
Coordinate
397
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 194 (in Homo sapiens)
Coordinate
194
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 577 (in Homo sapiens)
Coordinate
577
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 576 (in Homo sapiens)
Coordinate
576
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_990766.1
IntEnz
2.7.10.2
PRO
Q00944
PDB
1PV3
,
2J0L
,
2J0M
,
4D5H
,
1KTM
,
6TY4
,
6TY3
,
4D4R
,
2JKK
,
4D5K
,
6CB0
,
2JKM
,
4D4S
,
2L6F
,
4BRX
,
2JKO
,
6GCR
,
3ZDT
,
2L6H
,
2L6G
,
2AEH
,
4C7T
,
2JKQ
,
4D4V
,
4D55
,
1QVX
,
6GCX
,
6GCW
,
4D4Y
,
2J0J
,
2AL6
,
4CYE
,
2J0K
,
4D58
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00944
11
phospho-pY-PTK2 [cytosol]
(R-GGA-9632393)
phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(R-GGA-8874613)
phospho-p-Y194,Y397-PTK2 [cytosol]
(R-GGA-8874600)
phospho-p-5Y-PTK2 [cytosol]
(R-GGA-5218711)
phospho-p-5Y,S732-PTK2 [cytosol]
(R-GGA-5229006)
phospho-p-6Y,S732-PTK2 [cytosol]
(R-GGA-5218694)
PTK2(773-1052) [cytosol]
(R-GGA-202829)
PTK2(1-772) [cytosol]
(R-GGA-202827)
PTK2 [cytosol]
(R-GGA-201621)
phospho-p-Y397-PTK2 [cytosol]
(R-GGA-354068)
phospho-p-6Y-PTK2 [cytosol]
(R-GGA-354128)
0.656
3
UniProt:P61157 ACTR3
1
ARP3 [cytosol]
(R-BTA-419940)
0.612
5
UniProt:P49024 PAXI
0.609
2
UniProt:P08581 MET
7
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
MET [plasma membrane]
(R-HSA-419603)
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
0.602
5
UniProt:P00523 SRC
9
SRC [cytosol]
(R-GGA-9628701)
phospho-p-Y419-SRC [cytosol]
(R-GGA-8964276)
MyrG-SRC [plasma membrane]
(R-GGA-8876922)
Src [cytosol]
(R-GGA-3928468)
SRC-1 [plasma membrane]
(R-GGA-65043)
phospho-p-Y419-SRC [cytosol]
(R-GGA-377592)
phospho-MyrG,p-Y530-SRC [plasma membrane]
(R-GGA-377598)
phospho-MyrG-p-Y419-SRC [plasma membrane]
(R-GGA-1810408)
SRC-2 [cytosol]
(R-GGA-191648)
0.589
3
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