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phospho-SHC1 [cytosol]
Stable Identifier
R-GGA-8851895
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
p-Y317-SHC1-2, A0A1D5NYP8
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
phospho-SHC1 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by MET (Gallus gallus)
MET activates RAS signaling (Gallus gallus)
MET phosphorylates SHC1-2 (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
phospho-SHC1 [cytosol] (Gallus gallus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
phospho-SHC1 [cytosol] (Gallus gallus)
SHC1-2 bound to MET recruits GRB2:SOS1 (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
phospho-SHC1 [cytosol] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
phospho-SHC1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5NYP8
Gene Names
SHC1
Reference Genes
BioGPS Gene:395934 SHC1
ENSEMBL:ENSGALG00000039775
ENSEMBL:ENSGALG00010027922.1 SHC1
KEGG Gene (Gallus gallus):395934 SHC1
Monarch:395934 SHC1
NCBI Gene:395934 SHC1
Reference Transcript
RefSeq:NM_001293280.2 SHC1
Other Identifiers
395934
GO:0001525
GO:0001784
GO:0005068
GO:0005158
GO:0005159
GO:0005168
GO:0005886
GO:0006351
GO:0006355
GO:0007010
GO:0007155
GO:0007173
GO:0007507
GO:0008286
GO:0012501
GO:0023052
GO:0030036
GO:0030971
GO:0035556
GO:0042127
GO:0042742
GO:0043066
GO:0043410
GO:0045892
GO:0045893
GO:0046875
GO:0048009
GO:0048408
GO:0048856
GO:0060090
GO:0070374
GO:0071363
GO:0098542
GO:0098609
GO:0110165
GT_A_87_P037982
GT_A_87_P088641
Gga.2219.1.S1_at
GgaAffx.8748.1.S1_at
Participates
as a component of
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Gallus gallus)
Other forms of this molecule
SHC1 [plasma membrane]
SHC1 [plasma membrane]
SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
Inferred From
pY-SHC1 [cytosol]
(Homo sapiens)
p-Y317-SHC1-2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 317 (in Homo sapiens)
Coordinate
317
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_001280209.1
OpenTargets
ENSG00000160691
Ensembl
ENSGALT00010067680
,
ENSGALG00010027922
,
ENSGALP00010041423
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