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CYLD [cytosol]
Stable Identifier
R-GGA-741420
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NH67
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
CYLD:K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
K63polyUb-RIPK1 is deubiquitinated (Gallus gallus)
RIPK1 deubiquitinases [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
MIB2 binds CYLD (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
OPTN recruits CYLD to the TNFR1 complex (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Gallus gallus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Gallus gallus)
CYLD:SPATA2:LUBAC [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Gallus gallus)
CYLD:SPATA2:LUBAC [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
TNFR1-induced proapoptotic signaling (Gallus gallus)
TRADD:TRAF2:RIP1 complex binds FADD (Gallus gallus)
RIPK1 deubiquitinases [cytosol] (Gallus gallus)
CYLD [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NH67
Reference Genes
ENSEMBL:ENSGALG00000003753
Participates
as a component of
CYLD:K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Gallus gallus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
CYLD:SPATA2:LUBAC [cytosol] (Gallus gallus)
as an input of
OPTN recruits CYLD to the TNFR1 complex (Gallus gallus)
MIB2 binds CYLD (Gallus gallus)
as a member of
RIPK1 deubiquitinases [cytosol] (Gallus gallus)
Other forms of this molecule
K48polyUb-K338, K530-CYLD [cytosol]
phospho-p-S418-CYLD [cytosol]
Inferred From
CYLD [cytosol]
(Homo sapiens)
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