Reactome | RPL13 [cytosol]

RPL13 [cytosol]

Stable Identifier

R-GGA-72410

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPL13, P41125

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL13 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL13 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL13 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL13 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL13 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:P41125

Gene Names

RPL13

Reference Genes

BioGPS Gene:395849 RPL13

ENSEMBL:ENSGALG00000006179

ENSEMBL:ENSGALG00010007998.1 RPL13

ENSEMBL:ENSGALG00015011287 RPL13

KEGG Gene (Gallus gallus):395849 RPL13

Monarch:395849 RPL13

NCBI Gene:395849 RPL13

Reference Transcript

RefSeq:NM_204999.1 RPL13

Other Identifiers

395849

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005730

GO:0005737

GO:0005783

GO:0005829

GO:0005840

GO:0006412

GO:0022625

GO:0022626

GO:0043226

GO:0045202

GO:0048856

GO:0060348

GO:1990904

GT_A_87_P009799

GT_Xhyb_Chicken_CN220005_1610

GT_Xhyb_Chicken_CN225207_3168

Gga.4040.1.S1_at

Participates

as a component of

Inferred From

RPL13 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_990330.1

OpenTargets

ENSG00000167526

Ensembl

ENSGALT00010019067, ENSGALP00010010616, ENSGALG00010007998

PRO

P41125

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