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CDK7 [nucleoplasm]
Stable Identifier
R-GGA-69218
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
E1C8L2
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
Mitotic G1 phase and G1/S transition (Gallus gallus)
G1 Phase (Gallus gallus)
Cyclin D associated events in G1 (Gallus gallus)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
G1/S Transition (Gallus gallus)
Cyclin E associated events during G1/S transition (Gallus gallus)
CAK-mediated phosphorylation of Cyclin E:Cdk2 (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Mitotic G2-G2/M phases (Gallus gallus)
G2/M Transition (Gallus gallus)
Cyclin A/B1/B2 associated events during G2/M transition (Gallus gallus)
CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
S Phase (Gallus gallus)
Cyclin A:Cdk2-associated events at S phase entry (Gallus gallus)
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
DNA Repair (Gallus gallus)
Nucleotide Excision Repair (Gallus gallus)
Global Genome Nucleotide Excision Repair (GG-NER) (Gallus gallus)
Formation of Incision Complex in GG-NER (Gallus gallus)
Recruitment of XPA and release of CAK (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TFIIH binds GG-NER site to form a verification complex (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Gallus gallus)
Dual incision in TC-NER (Gallus gallus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Gallus gallus)
TC-NER incision complex [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Gallus gallus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)
TC-NER pre-incision complex [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC5 and RPA bind TC-NER site (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Formation of TC-NER Pre-Incision Complex (Gallus gallus)
Active RNA Pol II complex transcribes lesion-containing DNA template (Gallus gallus)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC6 binds stalled RNA Pol II (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC8 (CSA) binds stalled RNA Pol II (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Pol II initiates transcription from damaged DNA template (Gallus gallus)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
UVSSA:USP7 deubiquitinates ERCC6 (Gallus gallus)
TC-NER pre-incision complex [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Gallus gallus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Gallus gallus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Gallus gallus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Gallus gallus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase I Transcription (Gallus gallus)
RNA Polymerase I Promoter Clearance (Gallus gallus)
RNA Polymerase I Promoter Escape (Gallus gallus)
Elongation of pre-rRNA transcript (Gallus gallus)
RNA Polymerase I promoter escape complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Gallus gallus)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase I promoter escape complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase I Transcription Initiation (Gallus gallus)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Gallus gallus)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase I Transcription Termination (Gallus gallus)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Gallus gallus)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Gallus gallus)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Gallus gallus)
RNA Polymerase I promoter escape complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Gallus gallus)
RNA Polymerase I promoter escape complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Transcription of DNA Repair Genes (Gallus gallus)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Gallus gallus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Gallus gallus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Gallus gallus)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Gallus gallus)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Gallus gallus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Transcriptional regulation by RUNX1 (Gallus gallus)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Gallus gallus)
RUNX1 binds the core TAL1 complex (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Pol II CTD phosphorylation and interaction with CE (Gallus gallus)
Activation of GT (Gallus gallus)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Gallus gallus)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Phosphorylation (Ser5) of RNA pol II CTD (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II CTD (phosphorylated) binds to CE (Gallus gallus)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Pre-transcription Events (Gallus gallus)
Abortive Initiation After Second Transition (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Abortive Initiation Before Second Transition (Gallus gallus)
Pol II Promoter Escape Complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Abortive initiation after formation of the first phosphodiester bond (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Fall Back to Closed Pre-initiation Complex (Gallus gallus)
pol II closed pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II open pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Transcription Elongation (Gallus gallus)
Addition of nucleotides leads to transcript elongation (Gallus gallus)
Elongation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Formation of the Early Elongation Complex (Gallus gallus)
Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Gallus gallus)
RNA Polymerase II Promoter Escape (Gallus gallus)
Addition of Nucleotides 5 through 9 on the growing Transcript (Gallus gallus)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Gallus gallus)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Addition of nucleotides between position +11 and +30 (Gallus gallus)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Gallus gallus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Addition of the third nucleotide on the nascent transcript (Gallus gallus)
pol II transcription complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Unwinding DNA for the nascent transcript (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Unwinding of DNA for the Nascent Transcript: Second Transition (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Promoter Opening: First Transition (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II closed pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II open pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Transcription Initiation (Gallus gallus)
NTP Binds Active Site of RNA Polymerase II (Gallus gallus)
Pol II initiation complex [nucleoplasm] (Gallus gallus)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II open pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Gallus gallus)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II transcription complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Gallus gallus)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Pol II initiation complex [nucleoplasm] (Gallus gallus)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Gallus gallus)
Formation of the closed pre-initiation complex (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
pol II closed pre-initiation complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II transcribes snRNA genes (Gallus gallus)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Gallus gallus)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Integrator complex processes the 3' end of snRNA (Gallus gallus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Pre-snRNA is elongated and capped with 7-methylguanosine (Gallus gallus)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Gallus gallus)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Gallus gallus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Metabolism of RNA (Gallus gallus)
mRNA Capping (Gallus gallus)
Activation of GT (Gallus gallus)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex formation (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex (initial) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Dissociation of transcript with 5'-GMP from GT (Gallus gallus)
Capping complex (GpppN..) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Formation of the CE:GMP intermediate complex (Gallus gallus)
Capping complex (intermediate) [nucleoplasm] (Gallus gallus)
Covalent CE:GMP intermediate complex [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex (hydrolyzed) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Gallus gallus)
Capping complex (hydrolyzed) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex (initial) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Polymerase II CTD (phosphorylated) binds to CE (Gallus gallus)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Gallus gallus)
Capping complex (intermediate) [nucleoplasm] (Gallus gallus)
Covalent CE:GMP intermediate complex [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
Capping complex (GpppN..) [nucleoplasm] (Gallus gallus)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Gallus gallus)
TFIIH [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
CDK7 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1C8L2
Reference Genes
ENSEMBL:ENSGALG00000014790
Participates
as a component of
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Gallus gallus)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Gallus gallus)
CAK [nucleoplasm] (Gallus gallus)
Inferred From
CDK7 [nucleoplasm]
(Homo sapiens)
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