Reactome | RPA heterotrimer [nucleoplasm]

RPA heterotrimer [nucleoplasm]

Stable Identifier

R-GGA-68462

Type

Complex

Species

Gallus gallus

Compartment

nucleoplasm

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

RPA1 [nucleoplasm] (Gallus gallus)
RPA2 [nucleoplasm] (Gallus gallus)
RPA3 [nucleoplasm] (Gallus gallus)

Participates

as a component of

PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Gallus gallus)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Gallus gallus)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Gallus gallus)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Gallus gallus)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Gallus gallus)
HSF1:RPA [nucleoplasm] (Gallus gallus)
RPA:DNA containing single strand gap [nucleoplasm] (Gallus gallus)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Gallus gallus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Gallus gallus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Gallus gallus)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
RPA complexed to ssDNA [nucleoplasm] (Gallus gallus)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Gallus gallus)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Gallus gallus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Gallus gallus)

as an input of

RPA1 binds HSF1 (Gallus gallus)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Gallus gallus)
The complex of ATR and ATRIP is recruited to ICL-DNA (Gallus gallus)
ERCC5 and RPA bind TC-NER site (Gallus gallus)
Formation of the pre-incision complex in GG-NER (Gallus gallus)
Stalling of DNA replication fork and RPA binding (Gallus gallus)
Association of RPA complexes with ssDNA at resected DNA DSBs (Gallus gallus)

as an output of

PPP4C:PPP4R2 dephosphorylates RPA2 (Gallus gallus)

Inferred From

RPA heterotrimer [nucleoplasm] (Homo sapiens)

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