Reactome | TMED2 [transport vesicle]

TMED2 [transport vesicle]

Stable Identifier

R-GGA-6808806

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

transport vesicle

Synonyms

A0A3Q2U769

Locations in the PathwayBrowser

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Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Asparagine N-linked glycosylation (Gallus gallus)
    - Transport to the Golgi and subsequent modification (Gallus gallus)
      - ER to Golgi Anterograde Transport (Gallus gallus)
        
        COPI-mediated anterograde transport (Gallus gallus)
        
        ARFGAPs stimulate ARF GTPase activity (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)

Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - ER to Golgi Anterograde Transport (Gallus gallus)
    - COPI-mediated anterograde transport (Gallus gallus)
      - ARFGAPs stimulate ARF GTPase activity (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Gallus gallus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Gallus gallus)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Gallus gallus)
        
        TMED2:TMED10 tetramer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Gallus gallus)
    - Golgi-to-ER retrograde transport (Gallus gallus)
      - COPI-dependent Golgi-to-ER retrograde traffic (Gallus gallus)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Gallus gallus)
        
        Golgi-to-ER cargo [transport vesicle] (Gallus gallus)
        
        SURF4:p24 complex [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Gallus gallus)
        
        Golgi-to-ER cargo [transport vesicle] (Gallus gallus)
        
        SURF4:p24 complex [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Gallus gallus)
        
        Golgi-to-ER cargo [transport vesicle] (Gallus gallus)
        
        SURF4:p24 complex [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Gallus gallus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Gallus gallus)
        
        Golgi-to-ER cargo [transport vesicle] (Gallus gallus)
        
        SURF4:p24 complex [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)
        
        p24 dimers [transport vesicle] (Gallus gallus)
        
        TMED2 dimer [transport vesicle] (Gallus gallus)
        
        TMED2 [transport vesicle] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2U769

Reference Genes

ENSEMBL:ENSGALG00000003307

Participates

as a component of

Other forms of this molecule

TMED2 [Golgi membrane]

TMED2 [ER to Golgi transport vesicle membrane]

TMED2 [endoplasmic reticulum membrane]

TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED2 [transport vesicle] (Homo sapiens)

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