Reactome | INTS14 [nucleoplasm]

INTS14 [nucleoplasm]

Stable Identifier

R-GGA-6807412

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

VWA9, Q5ZK21

Locations in the PathwayBrowser

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Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase II Transcription (Gallus gallus)
  - RNA polymerase II transcribes snRNA genes (Gallus gallus)
    - Integrator complex processes the 3' end of snRNA (Gallus gallus)
      - Integrator [nucleoplasm] (Gallus gallus)
        
        INTS14 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS14 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS14 [nucleoplasm] (Gallus gallus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS14 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS14 [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q5ZK21

Gene Names

INTS14

Reference Genes

BioGPS Gene:415540 INTS14

CTD Gene:415540 INTS14

ENSEMBL:ENSGALG00000007491

ENSEMBL:ENSGALG00010017815.1 INTS14

ENSEMBL:ENSGALG00015023335 INTS14

KEGG Gene (Gallus gallus):415540 INTS14

Monarch:415540 INTS14

NCBI Gene:415540 INTS14

Reference Transcript

Other Identifiers

415540

GO:0005634

GO:0016073

GO:0032039

GO:0034472

GO:0043226

GT_A_87_P036526

GgaAffx.12366.1.S1_s_at

Participates

as a component of

Integrator [nucleoplasm] (Gallus gallus)

Inferred From

VWA9 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_015147579.1, XP_015147580.1, NP_001005825.1

OpenTargets

ENSG00000138614

Ensembl

ENSGALP00010025550, ENSGALG00010017815, ENSGALT00010043060

PRO

Q5ZK21

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