Reactome | INTS8 [nucleoplasm]

INTS8 [nucleoplasm]

Stable Identifier

R-GGA-6807409

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

INTS8, A0A1D5P482

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase II Transcription (Gallus gallus)
  - RNA polymerase II transcribes snRNA genes (Gallus gallus)
    - Integrator complex processes the 3' end of snRNA (Gallus gallus)
      - Integrator [nucleoplasm] (Gallus gallus)
        
        INTS8 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS8 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS8 [nucleoplasm] (Gallus gallus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS8 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS8 [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5P482

Gene Names

INTS8

Reference Genes

BioGPS Gene:420230 INTS8

ENSEMBL:ENSGALG00000037955

ENSEMBL:ENSGALG00010012366.1 INTS8

KEGG Gene (Gallus gallus):420230 INTS8

Monarch:420230 INTS8

NCBI Gene:420230 INTS8

Reference Transcript

RefSeq:NM_001040228.2 INTS8

Other Identifiers

420230

GO:0005634

GO:0016073

GO:0032039

GO:0034472

GO:0043226

GT_A_87_P255793

Gga.2265.2.S1_s_at

Participates

as a component of

Integrator [nucleoplasm] (Gallus gallus)

Inferred From

INTS8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001035318.1

OpenTargets

ENSG00000164941

Ensembl

ENSGALG00010012366, ENSGALP00010017242, ENSGALT00010029633

Cite Us!