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IL35 [extracellular region]
Stable Identifier
R-GGA-622267
Type
Complex
Species
Gallus gallus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-12 family signaling (Gallus gallus)
Interleukin-35 Signalling (Gallus gallus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Gallus gallus)
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Gallus gallus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Gallus gallus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Gallus gallus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Gallus gallus)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Gallus gallus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
STAT1 associates with IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
STAT4 binds IL12RB2:IL12RB2 (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
p-STAT1 dissociates from IL6ST:IL6ST (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35 [extracellular region] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ghost homologue of EBI3 [extracellular region]
(Gallus gallus)
IL12A [extracellular region]
(Gallus gallus)
Participates
as a component of
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Gallus gallus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Gallus gallus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Gallus gallus)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Gallus gallus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Gallus gallus)
Inferred From
IL35 [extracellular region]
(Homo sapiens)
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