Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
DDB2 [nucleoplasm]
Stable Identifier
R-GGA-5696654
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
PAR-DDB2, Q5ZJL7
Locations in the PathwayBrowser
Expand all
DNA Repair (Gallus gallus)
Nucleotide Excision Repair (Gallus gallus)
Global Genome Nucleotide Excision Repair (GG-NER) (Gallus gallus)
DNA Damage Recognition in GG-NER (Gallus gallus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Dual Incision in GG-NER (Gallus gallus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Gallus gallus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Formation of Incision Complex in GG-NER (Gallus gallus)
CHD1L is recruited to GG-NER site (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Formation of the pre-incision complex in GG-NER (Gallus gallus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
RNF111 ubiquitinates SUMOylated XPC (Gallus gallus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Recruitment of XPA and release of CAK (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
SUMOylation of XPC (Gallus gallus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
TFIIH binds GG-NER site to form a verification complex (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Gallus gallus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Gallus gallus)
PAR-UV-DDB [nucleoplasm] (Gallus gallus)
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
DDB2 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q5ZJL7
Gene Names
DDB2
Reference Genes
BioGPS Gene:423185 DDB2
ENSEMBL:ENSGALG00000008218
ENSEMBL:ENSGALG00015012175 DDB2
KEGG Gene (Gallus gallus):423185 DDB2
Monarch:423185 DDB2
NCBI Gene:423185 DDB2
Reference Transcript
RefSeq:NM_001039301.1 DDB2
RefSeq:XM_015287023.1 DDB2
RefSeq:XM_015287024.1 DDB2
RefSeq:XM_015287022.1 DDB2
RefSeq:XM_015287025.1 DDB2
Participates
as a component of
DDB1:PAR-DDB2 [nucleoplasm] (Gallus gallus)
Other forms of this molecule
DDB2 [nucleoplasm]
DDB2 [nucleoplasm]
Inferred From
PAR-DDB2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
L-glutamyl-5-poly(ADP-ribose) at unknown position
PsiMod Name
L-glutamyl-5-poly(ADP-ribose)
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Cross References
RefSeq
XP_015142510.1
,
NP_001034390.1
,
XP_015142511.1
,
XP_015142508.1
,
XP_015142509.1
OpenTargets
ENSG00000134574
PRO
Q5ZJL7
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text